borne illness in the town. The COVID-19 pandemic had a significant economic and social impact on the Kingdom of Saudi Arabia. This study explored various factors influencing the COVID-19 vaccination intention and the applicability of the health belief model (HBM) to explore vaccination intention among the population of Saudi Arabia. This is an online survey conducted between January 6, 2021, and January 19, 2021, using a Google form questionnaire among Saudi population. The questionnaire aimed to assess the factors that influence the intent to receive the vaccine, by evaluating demographic details, COVID-19 experience and health self-assessment, acceptability of COVID-19 vaccination and preferences and health belief regarding COVID-19 illness and vaccination. The survey generated a total of 1333 responses from all over the 13 provinces of the Kingdom. The participants had mixed perceptions regarding the susceptibility and severity of COVID-19. A total of 959 (71.9%) subjects responded positively to COVID-19 vaccine intent. Those with >15,000 SR per month income, no past exposure to COVID-19, and comorbidities reported significantly higher intention to take vaccination (p<0.05). Among the HBM variables, the perceived susceptibility construct (OR=3.82, 95% CI 1.64-8.94) and perceived benefit construct (OR=7.59, CI 1.65-34.86) were important facilitators for a definite intention to vaccinate. The perceived barriers construct (safety [OR= 0.062, CI 0.03-0.15]; side effects of the vaccine [OR=0.31, CI 0.13-0.75]) and cues to action construct (OR=0.32, CI 0.13-0.77) were the significant factors hindering the uptake of COVID-19 vaccine. However, the perceived severity construct did not play an important role in predicting definite intention to receive the COVID-19 vaccine in the Saudi population. The study has important implications for promoting COVID-19 vaccination uptake among the population of Saudi Arabia.The study has important implications for promoting COVID-19 vaccination uptake among the population of Saudi Arabia. In-hospital mortality after emergency coronary artery bypass grafting (CABG) remains an important issue that has needed considerable attention in recent years as the mortality rate is still high and prevention factors are not yet optimal. Our study presents the first largest cohort of emergency CABG from one large institution in Vietnam with the primary aim of comparing a large variety of pre-, intra-and post-operative parameters between in-hospital mortality patients and in-hospital survival patients and investigate risk factors of in-hospital mortality in patients undergoing emergency CABG. We conducted a retrospective evaluation of prospectively collected data in patients undergoing emergency CABG at the Hanoi Heart Hospital (Hanoi, Vietnam) from January 1, 2017, to December 31, 2019. Primary outcome variable was in-hospital mortality. A total of 71 patients were included in final analysis. The mean age of the cohort was 68.68 years (± 9.28, range 38-86). The mean weight, height and body mass index wortality rate after emergency CABG was relatively high. An optimal preventive strategy in emergency CABG management should target significant factors combined with other previously identified risk factors to reduce in-hospital mortality.Our hospital mortality rate after emergency CABG was relatively high. An optimal preventive strategy in emergency CABG management should target significant factors combined with other previously identified risk factors to reduce in-hospital mortality. Atypical chest pain in some outpatients could derive from mental disorders. It is necessary for them to have a preliminary emotional assessment in the outpatient department of Cardiology before psychiatric outpatient visits. This study included 122 Chinese outpatients with atypical chest pain in the department of Cardiology. They accepted routine examinations, including treadmill test, and were judged by the three-question method as highly likely to have emotional disorders. Then, a standard questionnaire package containing the Chinese version of the seven-item scale for General Anxiety Disorder (GAD-7), Self-rating Anxiety Scale (SAS), the nine-item Patient Health Questionnaire (PHQ-9) and Self-rating Depression Scale (SDS) was administered to evaluate anxiety and depression. The percentages of anxiety evaluated by GAD-7 and SAS were 62.3% and 26.2%, respectively. Analogously, the assessment by PHQ-9 showed a significantly higher percentage of depression than that by SDS (61.5% vs 29.5%) ( < 0.05) Cardiology before psychiatric visits. Temporary transvenous cardiac pacing (TTCP) can lead to potential penetration and occasional perforation of the right ventricular wall. No study to date has analyzed the effect of TTCP on myocardial injury by cardiac troponin (cTn) measurement. The present study was designed to investigate perioperative myocardial injury in elective TTCP in noncardiac surgical settings. This retrospective study investigated the data collected from August 2018 through March 2020 from 22 eligible patients who underwent elective TTCP for noncardiac procedures. The patients had a median age of 66 (50-83) years; six (27.3%) of them were women, and all of them had a baseline cTn <1 upper reference limit (URL). Cardiac biomarker assays were performed before and after TTCP, and their results were compared. After TTCP, cTn > 1 URL was detected in 20 (91%, N=22) patients. Among these 22 patients, paired -test comparing assay results before and after TTCP lead insertion showed a mean cTn elevation of 3.599 URL (95% CI 1.566 to 5.632, P<0.01), and a mean creatine kinase-MB isoform elevation of 0.1550 URL (95% CI -0.01239 to 0.3224, P>0.05). The study demonstrates a high incidence of myocardial injury associated with TTCP, which should be a matter of concern for the involved physicians.The study demonstrates a high incidence of myocardial injury associated with TTCP, which should be a matter of concern for the involved physicians. Tripterygium glycoside (TG) has been suggested to have protective effects on the diseases of the central nervous system including Alzheimer's disease (AD). The mechanisms involving lncRNA-associated competing endogenous RNAs (ceRNAs) were shown to play important roles in the development of AD. Pluronic F-68 Hydrotropic Agents chemical However, the ceRNA mechanism of TG in treating AD is still unknown. Thus, we aimed to explore the ceRNA mechanism in the treatment of AD with TG. A total of 32 C57BL/6J mice were administered 3 µL of Aβ (dual side, 1 mg/mL) by a single stereotactic injection in the brain to conduct AD mouse model. AD mouse models were randomly selected and divided into the AD+normal saline (NS) group (n=16) and the AD+TG group (n=16). The expression data of lncRNAs, mRNAs, and miRNAs in the hippocampus of mice from AD+NS group (n=3) and the AD+TG group (n=3) were obtained by microarray analysis. The MuTaME method was used to predict the ceRNA regulatory network. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed using the DAVID database.